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KMID : 0380620210530020139
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Korean Journal of Food Science and Technology
2021 Volume.53 No. 2 p.139 ~ p.148
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An overview of the regulatory effect of vitamin D supplementation on atopic dermatitis
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Sung Dong-Eun
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Abstract
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Atopic dermatitis is a chronic, recurrent, inflammatory skin disease that is a well-known allergic disease with severe itching, making daily life difficult. Since the immunomodulatory action of vitamin D has been reported, several researchers have attempted to determine the correlation between vitamin D and atopic dermatitis. In this review, 41 articles meeting the inclusion criteria were selected and reviewed from the articles published to date. Several studies have reported that low vitamin D levels are associated with the onset of atopic dermatitis and severe atopic dermatitis, but the opinions remain conflicting. Similarly, there are conflicting opinions on the improvement effect of oral vitamin D supplementation on atopic dermatitis, but some possibilities have been suggested. To apply vitamin D as a therapeutic agent for atopic dermatitis, a more systematically designed experiment should be conducted, and an appropriate intake dose for an immunomodulatory function should be obtained.
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KEYWORD
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Vitamin D, atopic dermatitis, immunomodulation, vitamin D deficiency
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